Isomeric Separation of Permethylated Glycans by Porous Graphitic Carbon (PGC)-LC-MS/MS at High-Temperatures

Permethylation is a common derivatization method for MS-based glycomic analyses. Permethylation enhances glycan ionization efficiency in positive MS analysis and improves glycan structural stability. Recent biological glycomic studies have added to the growing body of knowledge and suggest the need...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Zhou, Shiyue, Huang, Yifan, Dong, Xue, Peng, Wenjing, Veillon, Lucas, Kitagawa, Daniel A. S., Aquino, Adelia J. A., Mechref, Yehia
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761069/
https://ncbi.nlm.nih.gov/pubmed/28475308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b00747
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