Modeling of Body Weight Metrics for Effective and Cost-Efficient Conventional Factor VIII Dosing in Hemophilia A Prophylaxis

The total body weight-based dosing strategy currently used in the prophylactic treatment of hemophilia A may not be appropriate for all populations. The assumptions that guide weight-based dosing are not valid in overweight and obese populations, resulting in overdosing and ineffective resource util...

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Vydáno v:Pharmaceutics
Hlavní autoři: McEneny-King, Alanna, Chelle, Pierre, Henrard, Severine, Hermans, Cedric, Iorio, Alfonso, Edginton, Andrea N.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750653/
https://ncbi.nlm.nih.gov/pubmed/29039750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics9040047
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