The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction

BACKGROUND: Isoenzymes CYP2D6 and CYP3A4, the activity of which varies widely, are involved in metabolism of haloperidol and may influence its profile of efficacy and safety. OBJECTIVE: The primary aim of this study was to estimate the relationship between CYP3A5 gene polymorphism, activity of the C...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Main Authors: Zastrozhin, Mikhail Sergeevich, Grishina, Elena Anatolievna, Ryzhikova, Kristina Anatolievna, Smirnov, Valery Valerievich, Savchenko, Ludmila Mikhailovna, Bryun, Evgeny Alekseevich, Sychev, Dmitry Alekseevich
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749387/
https://ncbi.nlm.nih.gov/pubmed/29343979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S144503
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