Human CYP2A13 and CYP2F1 Mediate Naphthalene Toxicity in the Lung and Nasal Mucosa of CYP2A13/2F1-Humanized Mice

BACKGROUND: The potential carcinogenicity of naphthalene (NA), a ubiquitous environmental pollutant, in human respiratory tract is a subject of intense debate. Chief among the uncertainties in risk assessment for NA is whether human lung CYP2A13 and CYP2F1 can mediate NA’s respiratory tract toxicity...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Environ Health Perspect
Prif Awduron: Li, Lei, Carratt, Sarah, Hartog, Matthew, Kovalchuk, Nataliia, Jia, Kunzhi, Wang, Yanan, Zhang, Qing-Yu, Edwards, Patricia, Van Winkle, Laura, Ding, Xinxin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Environmental Health Perspectives 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743450/
https://ncbi.nlm.nih.gov/pubmed/28599267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP844
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