Statin Therapy Negatively Impacts Skeletal Muscle Regeneration and Cutaneous Wound Repair in Type 1 Diabetic Mice

Those with diabetes invariably develop complications including cardiovascular disease (CVD). To reduce their CVD risk, diabetics are generally prescribed cholesterol-lowering 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors (i.e., statins). Statins inhibit cholesterol biosynthesis, but also...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Rebalka, Irena A., Cao, Andrew W., Raleigh, Matthew J., Henriksbo, Brandyn D., Coleman, Samantha K., Schertzer, Jonathan D., Hawke, Thomas J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742241/
https://ncbi.nlm.nih.gov/pubmed/29311999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01088
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