Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue

Tumors from colorectal cancer (CRC) are generally immunogenic and commonly infiltrated with T lymphocytes. However, the details of the adaptive immune reaction to these tumors are poorly understood. We have accrued both colon tumor samples and adjacent healthy mucosal samples from 15 CRC patients to...

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Udgivet i:Cancer Immunol Immunother
Main Authors: Sherwood, Anna M., Emerson, Ryan O., Scherer, Dominique, Habermann, Nina, Buck, Katharina, Staffa, Jürgen, Desmarais, Cindy, Halama, Niels, Jaeger, Dirk, Schirmacher, Peter, Herpel, Esther, Kloor, Matthias, Ulrich, Alexis, Schneider, Martin, Ulrich, Cornelia M., Robins, Harlan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714653/
https://ncbi.nlm.nih.gov/pubmed/23771160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1446-2
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