Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation

AIM: Interleukin-27 (IL-27) is involved in different inflammatory diseases; however, its role in atherosclerosis is unclear. In this study we investigated the expression of IL-27 and its receptor in patients with carotid atherosclerosis and if IL-27 could modulate the inflammatory effects of the NLR...

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Bibliographic Details
Published in:PLoS One
Main Authors: Gregersen, Ida, Sandanger, Øystein, Askevold, Erik T., Sagen, Ellen Lund, Yang, Kuan, Holm, Sverre, Pedersen, Turid M., Skjelland, Mona, Krohg-Sørensen, Kirsten, Hansen, Trond Vidar, Dahl, Tuva Børresdatter, Otterdal, Kari, Espevik, Terje, Aukrust, Pål, Yndestad, Arne, Halvorsen, Bente
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703457/
https://ncbi.nlm.nih.gov/pubmed/29176764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188387
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