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Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a genetic disease characterised by skeletal muscle degeneration and progressive muscle wasting, which is caused by loss-of-function mutations in the DMD gene that encodes for the protein dystrophin. Dystrophin has critical roles in myofiber stability and integrit...
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Опубликовано в: : | NPJ Regen Med |
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Главные авторы: | , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Nature Publishing Group
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703417/ https://ncbi.nlm.nih.gov/pubmed/29188075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjregenmed.2016.6 |
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