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Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a genetic disease characterised by skeletal muscle degeneration and progressive muscle wasting, which is caused by loss-of-function mutations in the DMD gene that encodes for the protein dystrophin. Dystrophin has critical roles in myofiber stability and integrit...

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Enregistré dans:
Détails bibliographiques
Publié dans:NPJ Regen Med
Auteurs principaux: Dumont, Nicolas A, Rudnicki, Michael A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703417/
https://ncbi.nlm.nih.gov/pubmed/29188075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjregenmed.2016.6
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