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Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
Delivering isotopic tracers for metabolic studies in rodents without overt stress is challenging. Current methods achieve low label enrichment in proteins and lipids. Here, we report noninvasive introduction of (13)C(6)-glucose via a stress-free, ad libitum liquid diet. Using NMR and ion chromatogra...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696342/ https://ncbi.nlm.nih.gov/pubmed/29158483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01518-z |
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