5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins

Glioblastoma (GBM) contains diverse microenvironments with uneven distributions of oncogenic alterations and signaling networks. The diffusely infiltrative properties of GBM result in residual tumor at neurosurgical resection margins, representing the source of relapse in nearly all cases and sugges...

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Udgivet i:Sci Rep
Main Authors: Ross, James L., Cooper, Lee A. D., Kong, Jun, Gutman, David, Williams, Merete, Tucker-Burden, Carol, McCrary, Myles R., Bouras, Alexandros, Kaluzova, Milota, Dunn, William D., Duong, Duc, Hadjipanayis, Constantinos G., Brat, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688093/
https://ncbi.nlm.nih.gov/pubmed/29142297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15849-w
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