A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling

Blood flow and mechanical forces in the ventricle are implicated in cardiac development and trabeculation. However, the mechanisms of mechanotransduction remain elusive. This is due in part to the challenges associated with accurately quantifying mechanical forces in the developing heart. We present...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Vedula, Vijay, Lee, Juhyun, Xu, Hao, Kuo, C.-C. Jay, Hsiai, Tzung K., Marsden, Alison L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679653/
https://ncbi.nlm.nih.gov/pubmed/29084212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005828
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