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Motifs for a deadly encounter

It is unknown how T cell antigen receptors from autoreactive CD8(+) T cells recognize self. A new paper shows that an unorthodox, low-affinity way of interacting with targets may be at the basis of autoimmunity.

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Detalles Bibliográficos
Publicado en:Nat Immunol
Main Authors: Coppieters, Ken T, von Herrath, Matthias G
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679406/
https://ncbi.nlm.nih.gov/pubmed/22344274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2226
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