Drug target ontology to classify and integrate drug discovery data

BACKGROUND: One of the most successful approaches to develop new small molecule therapeutics has been to start from a validated druggable protein target. However, only a small subset of potentially druggable targets has attracted significant research and development resources. The Illuminating the D...

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Vydáno v:J Biomed Semantics
Hlavní autoři: Lin, Yu, Mehta, Saurabh, Küçük-McGinty, Hande, Turner, John Paul, Vidovic, Dusica, Forlin, Michele, Koleti, Amar, Nguyen, Dac-Trung, Jensen, Lars Juhl, Guha, Rajarshi, Mathias, Stephen L., Ursu, Oleg, Stathias, Vasileios, Duan, Jianbin, Nabizadeh, Nooshin, Chung, Caty, Mader, Christopher, Visser, Ubbo, Yang, Jeremy J., Bologa, Cristian G., Oprea, Tudor I., Schürer, Stephan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679337/
https://ncbi.nlm.nih.gov/pubmed/29122012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13326-017-0161-x
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