Antiplasmodial Sesquiterpenoid Lactones from Trichospira verticillata: Structure Elucidation by Spectroscopic Methods and Comparison of Experimental and Calculated ECD Data

A dichloromethane extract of Trichospira verticillata from the Natural Products Discovery Institute was discovered to have good antiplasmodial activity (IC(50) ~5 μg/mL). After purification by liquid-liquid partition and C(18) reverse phase HPLC, four new germacranolide-type sesquiterpenoid lactones...

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Vydáno v:J Nat Prod
Hlavní autoři: Du, Yongle, Pearce, Kirk C., Dai, Yumin, Krai, Priscilla, Dalal, Seema, Cassera, Maria B., Goetz, Michael, Crawford, T. Daniel, Kingston, David G. I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679103/
https://ncbi.nlm.nih.gov/pubmed/28463001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.7b00247
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