In-Vitro Transcription analysis of NS5A from HCV-3a circulating in Pakistani patients with chronic hepatitis C and their differential response to antiviral therapy

OBJECTIVE: Mutations in HCV nonstructural protein 5A (NS5A) play a vital role in virus resistance. The aim of this study was to develop a correlation between NS5A mutations (genotype 3a) and virological response towards interferon alpha (IFN-α) plus ribavirin therapy. METHODS: In this study, which w...

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Bibliographic Details
Published in:Pak J Med Sci
Main Authors: Bhatti, Shameem, Manzoor, Sobia, Parvaiz, Fahed, Ashraf, Javed, Javed, Farakh
Format: Artigo
Language:Inglês
Published: Professional Medical Publications 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673740/
https://ncbi.nlm.nih.gov/pubmed/29142571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12669/pjms.335.12973
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