Human iPSC-derived cerebral organoids model cellular features of lissencephaly and reveal prolonged mitosis of outer radial glia

Classical lissencephaly is a genetic neurological disorder associated with mental retardation and intractable epilepsy, and Miller Dieker Syndrome (MDS) is the most severe form of the disease. In this study, to investigate effects of MDS on human progenitor subtypes that control neuronal output and...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Cell Stem Cell
Main Authors: Bershteyn, Marina, Nowakowski, Tomasz J., Pollen, Alex A., Di Lullo, Elizabeth, Nene, Aishwarya, Wynshaw-Boris, Anthony, Kriegstein, Arnold R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667944/
https://ncbi.nlm.nih.gov/pubmed/28111201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.12.007
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla