Pyrazinamide clearance is impaired among HIV/tuberculosis patients with high levels of systemic immune activation

Pyrazinamide is the main driver of sterilizing effect in the standard regimen in adults and older children, and this effect is concentration-dependent. Tuberculosis patients co-infected with human immunodeficiency virus (HIV) have an increased risk for poor tuberculosis treatment outcomes and advers...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Vinnard, Christopher, Ravimohan, Shruthi, Tamuhla, Neo, Pasipanodya, Jotam, Srivastava, Shashikant, Modongo, Chawangwa, Zetola, Nicola M., Weissman, Drew, Gumbo, Tawanda, Bisson, Gregory P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667771/
https://ncbi.nlm.nih.gov/pubmed/29095954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187624
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