Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion

The physiological relevance of Matrigel as a cell-culture substrate and in angiogenesis assays is often called into question. Here, we describe an array-based method for the identification of synthetic hydrogels that promote the formation of robust in vitro vascular networks for the detection of put...

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Udgivet i:Nat Biomed Eng
Main Authors: Nguyen, Eric H., Daly, William T., Le, Ngoc Nhi T., Farnoodian, Mitra, Belair, David G., Schwartz, Michael P., Lebakken, Connie S., Ananiev, Gene E., Saghiri, Mohammad Ali, Knudsen, Thomas B., Sheibani, Nader, Murphy, William L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667681/
https://ncbi.nlm.nih.gov/pubmed/29104816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-017-0096
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