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ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass
Chemotherapy promotes the development of cachexia, a debilitating condition characterized by muscle and fat loss. ACVR2B/Fc, an inhibitor of the Activin Receptor 2B signaling, has been shown to preserve muscle mass and prolong survival in tumor hosts, and to increase bone mass in models of osteogene...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665981/ https://ncbi.nlm.nih.gov/pubmed/29089584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15040-1 |
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