Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect

Aberrant alternative splicing and epigenetic changes are both associated with various cancers, but epigenetic regulation of alternative splicing in cancer is largely unknown. Here we report that the intragenic DNA methylation-mediated binding of Brother of Regulator of Imprinted Sites (BORIS) at the...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Singh, Smriti, Narayanan, Sathiya Pandi, Biswas, Kajal, Gupta, Amit, Ahuja, Neha, Yadav, Sandhya, Panday, Rajendra Kumar, Samaiya, Atul, Sharan, Shyam K., Shukla, Sanjeev
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664520/
https://ncbi.nlm.nih.gov/pubmed/29073069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708447114
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