Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers

OBJECTIVE: To determine the association between synaptic functioning as measured via neurogranin in CSF and cognition relative to established Alzheimer disease (AD) biomarkers in neurologically healthy older adults. METHODS: We analyzed CSF concentrations of neurogranin, β-amyloid (Aβ42), phosphoryl...

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Veröffentlicht in:Neurology
Hauptverfasser: Casaletto, Kaitlin B., Elahi, Fanny M., Bettcher, Brianne M., Neuhaus, John, Bendlin, Barbara B., Asthana, Sanjay, Johnson, Sterling C., Yaffe, Kristine, Carlsson, Cynthia, Blennow, Kaj, Zetterberg, Henrik, Kramer, Joel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664306/
https://ncbi.nlm.nih.gov/pubmed/28939668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004569
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