Liposome-encapsulated plasmid DNA of telomerase-specific oncolytic adenovirus with stealth effect on the immune system

Oncolytic virotherapy has the disadvantage of being unsuitable for systemic delivery due to immune elimination. Liposomal encapsulation is well-recognized to reduce immune elimination and enhance the stability of drugs in the bloodstream. In the present study, the potential of liposome-encapsulated...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Aoyama, Katsuyuki, Kuroda, Shinji, Morihiro, Toshiaki, Kanaya, Nobuhiko, Kubota, Tetsushi, Kakiuchi, Yoshihiko, Kikuchi, Satoru, Nishizaki, Masahiko, Kagawa, Shunsuke, Tazawa, Hiroshi, Fujiwara, Toshiyoshi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658411/
https://ncbi.nlm.nih.gov/pubmed/29074882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14717-x
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