Sampling to capture single-cell heterogeneity

Advances in single-cell technologies have highlighted the prevalence and biological significance of cellular heterogeneity. A critical question is how to design experiments that faithfully capture the true range of heterogeneity from samples of cellular populations. Here, we develop a data-driven ap...

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Udgivet i:Nat Methods
Main Authors: Rajaram, Satwik, Heinrich, Louise E., Gordan, John D., Avva, Jayant, Bonness, Kathy M., Witkiewicz, Agnieszka K., Malter, James S., Atreya, Chloe E., Warren, Robert S., Wu, Lani F., Altschuler, Steven J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658002/
https://ncbi.nlm.nih.gov/pubmed/28869755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4427
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