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Telomere DNA damage signaling regulates cancer stem cell evolution, epithelial mesenchymal transition, and metastasis
Chromosome ends are protected by telomeres that prevent DNA damage response and degradation. When telomeres become critically short, the DNA damage response is activated at chromosome ends which induces cellular senescence or apoptosis. Telomeres are protected by the double stranded DNA binding prot...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655185/ https://ncbi.nlm.nih.gov/pubmed/29113290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20960 |
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