The BDNF Val66Met polymorphism moderates the effect of cognitive reserve on 36-month cognitive change in healthy older adults

INTRODUCTION: Cognitive reserve (CR) and BDNF Val66Met are independently associated with the rate of cognitive decline in preclinical Alzheimer's disease. This study was designed to investigate the interactive effects of these variables on 36-month cognitive change in cognitively intact older a...

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Détails bibliographiques
Publié dans:Alzheimers Dement (N Y)
Auteurs principaux: Ward, David D., Andel, Ross, Saunders, Nichole L., Thow, Megan E., Klekociuk, Shannon Z., Bindoff, Aidan D., Vickers, James C.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651414/
https://ncbi.nlm.nih.gov/pubmed/29067339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2017.04.006
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