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Enzymatic separation of epimeric 4-C-hydroxymethylated furanosugars: Synthesis of bicyclic nucleosides

Conversion of D-glucose to 4-C-hydroxymethyl-1,2-O-isopropylidene-α-D-ribofuranose, which is a key precursor for the synthesis of different types of bicyclic/spiro nucleosides, led to the formation of an inseparable 1:1 mixture of the desired product and 4-C-hydroxymethyl-1,2-O-isopropylidene-α-D-xy...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Rana, Neha, Kumar, Manish, Khatri, Vinod, Maity, Jyotirmoy, Prasad, Ashok K
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647706/
https://ncbi.nlm.nih.gov/pubmed/29062429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.205
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