Comprehensive molecular characterization of pheochromocytoma and paraganglioma

We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCC/PGLs), a rare tumor type. Multi-platform integration revealed that PCC/PGLs are driven by diverse alterations affecting multiple genes and pathways. Pathogenic germline mutations occurred in eight PCC/P...

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Publicat a:Cancer Cell
Autors principals: Fishbein, Lauren, Leshchiner, Ignaty, Walter, Vonn, Danilova, Ludmila, Robertson, A. Gordon, Johnson, Amy R., Lichtenberg, Tara M., Murray, Bradley A., Ghayee, Hans K., Else, Tobias, Ling, Shiyun, Jefferys, Stuart R., de Cubas, Aguirre A., Wenz, Brandon, Korpershoek, Esther, Amelio, Antonio L., Makowski, Liza, Rathmell, W. Kimryn, Gimenez-Roqueplo, Anne-Paule, Giordano, Thomas J., Asa, Sylvia L., Tischler, Arthur S., Pacak, Karel, Nathanson, Katherine L., Wilkerson, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643159/
https://ncbi.nlm.nih.gov/pubmed/28162975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.01.001
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