Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer

BACKGROUND: Monomeric laminin-γ2 in urine is a potential biomarker for bladder cancer. However, the current detection system uses an antibody that cannot discriminate between monomeric laminin-γ2 and the heterotrimeric γ2 chain of laminin-332, which may cause false-positive reactions. The present st...

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Bibliographische Detailangaben
Veröffentlicht in:Biomark Res
Hauptverfasser: Nakagawa, Masatoshi, Karashima, Takashi, Kamada, Masayuki, Yoshida, Eisaku, Yoshimura, Toru, Nojima, Masanori, Inoue, Keiji, Shuin, Taro, Seiki, Motoharu, Koshikawa, Naohiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640956/
https://ncbi.nlm.nih.gov/pubmed/29046806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-017-0109-4
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