High throughput quantification of apolipoproteins A‐I and B‐100 by isotope dilution MS targeting fast trypsin releasable peptides without reduction and alkylation

PURPOSE: Apolipoprotein A‐I (ApoA‐I) and apolipoprotein B‐100 (ApoB‐100) are amphipathic proteins that are strong predictors of cardiovascular disease risk. The traceable calibration of apolipoprotein assays is a persistent challenge, especially for ApoB‐100, which cannot be solubilized in purified...

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Publicat a:Proteomics Clin Appl
Autors principals: Parks, Bryan A, Schieltz, David M, Andrews, Michael L, Gardner, Michael S, Rees, Jon C, Toth, Christopher A, Jones, Jeffrey I, McWilliams, Lisa G, Kuklenyik, Zsuzsanna, Pirkle, James L, Barr, John R
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637893/
https://ncbi.nlm.nih.gov/pubmed/28296203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201600128
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