COLLAGEN V HAPLOINSUFFICIENCY IN A MURINE MODEL OF CLASSIC EHLERS-DANLOS SYNDROME IS ASSOCIATED WITH DEFICIENT STRUCTURAL AND MECHANICAL HEALING IN TENDONS

Classic Ehlers-Danlos syndrome (EDS) patients suffer from connective tissue hyperelasticity, joint instability, skin hyperextensibility, tissue fragility, and poor wound healing due to heterozygous mutations in COL5a1 or COL5a2 genes. This study investigated the roles of collagen V in establishing s...

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Publicat a:J Orthop Res
Autors principals: Johnston, Jessica M., Connizzo, Brianne K., Shetye, Snehal S., Robinson, Kelsey A., Huegel, Julianne, Rodriguez, Ashley B., Sun, Mei, Adams, Sheila M., Birk, David E., Soslowsky, Louis J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632109/
https://ncbi.nlm.nih.gov/pubmed/28387435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23571
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