Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

DnaK and other members of the 70-kilodalton heat-shock protein (hsp70) family promote protein folding, interaction, and translocation, both constitutively and in response to stress, by binding to unfoided polypeptide segments. These proteins have two functional units: a substrate-binding portion bin...

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Veröffentlicht in:Science
Hauptverfasser: Zhu, Xiaotian, Zhao, Xun, Burkholder, William F., Gragerov, Alexander, Ogata, Craig M., Gottesman, Max E., Hendrickson, Wayne A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629921/
https://ncbi.nlm.nih.gov/pubmed/8658133
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