IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production

The behaviors of lymphocytes, including CD4(+) T helper cells, are controlled on many levels by internal metabolic properties. Lipid metabolites have recently been ascribed a novel function as immune response modulators and perturbation of steroids pathways modulates inflammation and potentially pro...

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Опубликовано в: :Front Immunol
Главные авторы: Vigne, Solenne, Chalmin, Fanny, Duc, Donovan, Clottu, Aurélie S., Apetoh, Lionel, Lobaccaro, Jean-Marc A., Christen, Isabelle, Zhang, Juan, Pot, Caroline
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622150/
https://ncbi.nlm.nih.gov/pubmed/28993775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01184
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