Rilonacept maintains long-term inflammatory remission in patients with deficiency of the IL-1 receptor antagonist

BACKGROUND. Deficiency of IL-1 receptor antagonist (DIRA) is a rare autoinflammatory disease that presents with life-threatening systemic inflammation, aseptic multifocal osteomyelitis, and pustulosis responsive to IL-1–blocking treatment. This study was performed (a) to investigate rilonacept, a lo...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Garg, Megha, de Jesus, Adriana A., Chapelle, Dawn, Dancey, Paul, Herzog, Ronit, Rivas-Chacon, Rafael, Muskardin, Theresa L. Wampler, Reed, Ann, Reynolds, James C., Goldbach-Mansky, Raphaela, Sanchez, Gina A. Montealegre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621891/
https://ncbi.nlm.nih.gov/pubmed/28814674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94838
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