NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

Macrophages are attracted to developing tumors and can participate in immune surveillance to eliminate neoplastic cells. In response, neoplastic cells utilize NF-κB to suppress this killing activity, but the mechanisms underlying their self-protection remain unclear. Here, we report that this dynami...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Ratnam, Nivedita M., Peterson, Jennifer M., Talbert, Erin E., Ladner, Katherine J., Rajasekera, Priyani V., Schmidt, Carl R., Dillhoff, Mary E., Swanson, Benjamin J., Haverick, Ericka, Kladney, Raleigh D., Williams, Terence M., Leone, Gustavo W., Wang, David J., Guttridge, Denis C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617672/
https://ncbi.nlm.nih.gov/pubmed/28891811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91561
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