NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

Macrophages are attracted to developing tumors and can participate in immune surveillance to eliminate neoplastic cells. In response, neoplastic cells utilize NF-κB to suppress this killing activity, but the mechanisms underlying their self-protection remain unclear. Here, we report that this dynami...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Ratnam, Nivedita M., Peterson, Jennifer M., Talbert, Erin E., Ladner, Katherine J., Rajasekera, Priyani V., Schmidt, Carl R., Dillhoff, Mary E., Swanson, Benjamin J., Haverick, Ericka, Kladney, Raleigh D., Williams, Terence M., Leone, Gustavo W., Wang, David J., Guttridge, Denis C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617672/
https://ncbi.nlm.nih.gov/pubmed/28891811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91561
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