Protease activity of legumain is inhibited by an increase of cystatin E/M in the DJ-1-knockout mouse spleen, cerebrum and heart

Legumain (EC 3.4.22.34) is an asparaginyl endopeptidase. Legumain activity has been detected in various mouse tissues including the kidney, spleen and epididymis. Legumain is overexpressed in the majority of human solid tumors and transcription of the legumain gene is regulated by the p53 tumor supp...

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Vydáno v:Biochem Biophys Rep
Hlavní autoři: Yamane, Takuya, Kozuka, Miyuki, Yamamoto, Yoshio, Nakano, Yoshihisa, Nakagaki, Takenori, Ohkubo, Iwao, Ariga, Hiroyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614579/
https://ncbi.nlm.nih.gov/pubmed/28956004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.12.010
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