Post-pulse addition of trans-cyclohexane-1,2-diol improves electrotransfer mediated gene expression in mammalian cells

Electric field mediated gene transfer is facing a problem in expression yield due to the poor transfer across the nuclear envelope. Trans-cyclohexane-1,2-diol (TCHD) was shown to significantly increase chemically mediated transfection by collapsing the permeability barrier of the nuclear pore comple...

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Bibliographic Details
Published in:Biochem Biophys Rep
Main Authors: Pasquet, L., Bellard, E., Rols, M.P., Golzio, M., Teissie, J.
Format: Artigo
Language:Inglês
Published: Elsevier 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613639/
https://ncbi.nlm.nih.gov/pubmed/28955917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.07.012
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