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BDNF/TrkB axis activation promotes epithelial–mesenchymal transition in idiopathic pulmonary fibrosis

BACKGROUND: Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and disease. Here we investigated the expression and f...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Cherubini, Emanuela, Mariotta, Salvatore, Scozzi, Davide, Mancini, Rita, Osman, Giorgia, D’Ascanio, Michela, Bruno, Pierdonato, Cardillo, Giuseppe, Ricci, Alberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610541/
https://ncbi.nlm.nih.gov/pubmed/28938915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1298-1
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