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Additional K-ras mutation analysis and Plectin-1 staining improve the diagnostic accuracy of pancreatic solid mass in EUS-guided fine needle aspiration

BACKGROUND: One of the major genetic alterations in pancreatic ductal adenocarcinoma (PDAC) is the point mutation of K-ras gene. Plectin-1 was also recently identified as PDAC specific biomarker. The aim of this study was to investigate the improvement of diagnostic accuracy of endoscopic ultrasound...

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Pubblicato in:Oncotarget
Autori principali: Park, Joo Kyung, Paik, Woo Hyun, Song, Byeong Jun, Ryu, Ji Kon, Kim, Min A., Park, Jin Myung, Lee, Sang Hyub, Kim, Yong-Tae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610015/
https://ncbi.nlm.nih.gov/pubmed/28969083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16135
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