The amyloid precursor protein modulates α(2A)-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment

The amyloid precursor protein (APP) has long been appreciated for its role in Alzheimer’s disease (AD) pathology. However, less is known about the physiologic function of APP outside of AD. Particularly, whether and how APP may regulate functions of cell surface receptors, including GPCRs, remains l...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Zhang, Fang, Gannon, Mary, Chen, Yunjia, Zhou, Lufang, Jiao, Kai, Wang, Qin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2017
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602903/
https://ncbi.nlm.nih.gov/pubmed/28646018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700346R
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