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Oroxylin A inhibits colitis by inactivating NLRP3 inflammasome

NLRP3 inflammasome is a novel therapeutic target for inflammatory bowel disease (IBD). The aim of this study was to investigate the anti-inflammatory effect of a bioactive flavonoid—oroxylin A on the treatment of dextran sulfate sodium (DSS)-induced murine colitis via targeting NLRP3 inflammasome. I...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Wei, Liu, Xiuting, Zhang, Xin, Tang, Jingjing, Li, Zhiyu, Wang, Qing, Hu, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601702/
https://ncbi.nlm.nih.gov/pubmed/28938606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19440
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