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Zika virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins
Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact neurogenesis in vivo is not well understood. Here, by systematically introducing individual proteins encoded by ZIKV into the embryonic mouse cortex,...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Cell Stem Cell |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2017
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5600197/ https://ncbi.nlm.nih.gov/pubmed/28826723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.07.014 |
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