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PK/PD studies on non-selective PDE inhibitors in rats using cAMP as a marker of pharmacological response
In recent years, phosphodiesterase (PDE) inhibitors have been frequently tested for the treatment of experimental inflammatory and immune disorders. It is suggested that anti-inflammatory properties of PDE inhibitors are related to their ability to increase cAMP levels. The aim of this study was to...
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| Publicado no: | Naunyn Schmiedebergs Arch Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599463/ https://ncbi.nlm.nih.gov/pubmed/28730281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-017-1406-z |
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