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1,4-benzoquinone-induced STAT-3 hypomethylation in AHH-1 cells: Role of oxidative stress

Benzene, a known occupational and environmental contaminant, is associated with increased risk of leukemia. The objectives of this study were to elucidate the regulatory mechanism of the hypomethylated STAT3 involved in benzene toxicity in vitro. As 1,4-benzoquinone (1,4-BQ) is one of benzene’s majo...

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Bibliographic Details
Published in:Toxicol Rep
Main Authors: Yang, Jing, Bai, Wen-lin, Chen, Yu-jiao, Gao, Ai
Format: Artigo
Language:Inglês
Published: Elsevier 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598509/
https://ncbi.nlm.nih.gov/pubmed/28962422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.05.013
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