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Human carboxylesterase 2: Studies on the role of glycosylation for enzymatic activity

Human carboxylesterase 2 (hCES2) is a glycoprotein involved in the metabolism of drugs and several environmental xenobiotics, whose crystallization has been proved to be a challenging task. This limitation could partly be due to glycosylation heterogeneity and has delayed the disclosure of the 3D st...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Alves, Márcia, Lamego, Joana, Bandeiras, Tiago, Castro, Rute, Tomás, Hélio, Coroadinha, Ana Sofia, Costa, Júlia, Simplício, Ana Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598387/
https://ncbi.nlm.nih.gov/pubmed/28955811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.11.018
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