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Parkinson disease–associated LRRK2 G2019S transgene disrupts marrow myelopoiesis and peripheral Th17 response
Parkinson’s disease (PD) is a neurodegenerative disease, whereas Crohn’s disease is an inflammatory bowel disease. Interestingly, polymorphisms in the LRRK2 gene have been identified as risk factors for both diseases. LRRK2 G2019S is the most prevalent mutation found in PD. To gain insights into the...
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| Publicado no: | J Leukoc Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5597519/ https://ncbi.nlm.nih.gov/pubmed/28751472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1A0417-147RR |
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