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Parkinson disease–associated LRRK2 G2019S transgene disrupts marrow myelopoiesis and peripheral Th17 response

Parkinson’s disease (PD) is a neurodegenerative disease, whereas Crohn’s disease is an inflammatory bowel disease. Interestingly, polymorphisms in the LRRK2 gene have been identified as risk factors for both diseases. LRRK2 G2019S is the most prevalent mutation found in PD. To gain insights into the...

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Dades bibliogràfiques
Publicat a:J Leukoc Biol
Autors principals: Park, Jeongho, Lee, Jang-Won, Cooper, Scott C., Broxmeyer, Hal E., Cannon, Jason R., Kim, Chang H.
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597519/
https://ncbi.nlm.nih.gov/pubmed/28751472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1A0417-147RR
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