Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy

BACKGROUND: Acute myocardial infarction (AMI) is a severe disease causing heart failure and sudden death. Studies indicate that microRNAs (miRNAs) are involved in the pathophysiology of AMI. In the present study, we carefully explored the effects of miR-122 on myocardial hypoxia injury and its possi...

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Udgivet i:Med Sci Monit
Main Authors: Zhang, Zaiwei, Li, Hu, Chen, Shasha, Li, Ying, Cui, Zhiyuan, Ma, Jie
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2017
Fag:
Lab/In Vitro Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597036/
https://ncbi.nlm.nih.gov/pubmed/28871076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.902936
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