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Failures to further developing orphan medicinal products after designation granted in Europe: an analysis of marketing authorisation failures and abandoned drugs
OBJECTIVES: The research and development process in the field of rare diseases is characterised by many well-known difficulties, and a large percentage of orphan medicinal products do not reach the marketing approval. This work aims at identifying orphan medicinal products that failed the developmen...
保存先:
出版年: | BMJ Open |
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主要な著者: | , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
BMJ Publishing Group
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5595174/ https://ncbi.nlm.nih.gov/pubmed/28893754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-017358 |
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